PMC

Overall structure of the MIND complex as determined by EM and SAXS. (a) EM field of negatively stained MIND complex, with individual particles shown in the adjacent panel. (b) MIND particles visualized by low-angle rotary shadowing with platinum. (c) Two-dimensional class averages of the MIND particles (n = 251). (d) EM images of N- and C-terminal MBP-MIND fusion constructs. Additional density arising from the MBP protein is indicated with pink arrowheads. (e) SAXS scattering curve (red dots) of the MIND complex, with calculated model scattering curve (blue line). lexp, experimental scattering intensity; lcalc, calculated scattering intensity. (f) SAXS bead model reconstruction of the MIND complex. The structure shown represents results from a typical simulation. The various structural features referred to throughout the text are indicated on the model. (g) Averaged, filtered SAXS envelope derived from 30 separate ab initio reconstructions.

Results of the modified questionnaire of Westheimer (). (A) Body feeling after the dance class. (B) State of mind after the dance class. (C) Dance class impact on the quality of life in everyday life. (D) Duration of the impact on the quality of life. (E) Mobility after dance class.

Fig. 4. Time-lapse images of GFP–MinD movement in a field of rodA cells (WM1534). (A) Nomarski image of the field of cells. (B–H) Fluorescence images of the same field of cells at 10–20 s intervals. Indicated cells include class (i) cells with an asymmetric constriction with MinD oscillation perpendicular to the division plane (horizontal arrows); deeply constricted diplococci (class ii), apparently not fully septated with MinD oscillation perpendicular to the constriction (vertical arrows); and a nearly perfect sphere (class iii) with apparently random directionality of MinD movement (diagonal arrows).

Overall MIND Diet Score, Components, Foods and Nutrients and MRI Outcomes
A. The association between overall MIND diet score and thalamic volume using restricted cubic splines. Plotted values denote the mean difference in thalamic volume for an increase or decrease in MIND diet score relative to the 25^th percentile (scores of 7.5). Curves are additionally adjusted for age, sex, race, ethnicity, socio-economic status, physical activity, BMI, smoking status, disease duration, disease modifying therapy use and class, and total energy intake. Vertical dotted lines denote the 2.5^th, 25^th, 50^th, 75^th and 97.5^th percentile of MIND diet scores. B. Adjusted Spearman correlations between overall MIND diet score, components, foods, and nutrients of interest and MRI outcomes. Spearman correlations are adjusted for age, sex, race, ethnicity, socio-economic status, physical activity, BMI, smoking status, disease duration, disease modifying therapy use and class, and total energy intake. The “*” denotes p-values <0.05.